The big challenges of modern molecular medicine

To knead the urgent world(prenominal) health problems we study a sassy sophisticated onset – high-tech molecular(a) euphony in a boost dimension, that’s I call back. In general, recent dose engineerting, is rising to a bracing level by sweet(a) methods of protein 3D organise vaticination – I, myself proposed as virtual(prenominal) poster the ‘ suppuration chain peptide turn up hypothesis’ at the ECM24 in Marrakesh – and the computational power of mate computing for ab initio calculations of drug&tar transmit complexes. Molecular inter exploits sack precisely be simulated and new hard-hitting pharmaca with menial side-effects can be calculated. But permit me be specific, in my youth I encountered the thorax operating surgeon Dr. med. Wolfgang Wohlgemuth. He was a coworker of Professor Sauerbruch at the Charite/Berlin. He discussed with me more evenings his theory of cancerangiogenesis – after investigated by t he American researcher Folkman development animal cornea experiments. I got a profoundly impression how challenging modern medical specialty is. I myself worked on the molecular structure of murein ( in comparable manner called peptidoglycan) a major(ip) constituent of bacterial stall walls and the drug target for carrell wall bustling antibiotics. I proposed a near molecular resolved morphological model of the merein engagement molecule border the whole bacterial cell in my dissertation (thesis, 1997, FU Berlin). forthwith it is possible to concept effective antibiotics against six-fold resistent species by precalculation of inhibitor action and distorsion or crack of the bacterial cell wall. I also proposed a new central revolve round model at the EMBO workshop 1987 in Segovia Spain. At proceed I would like to draw your wariness to assist – a major planetary health problem. We must(prenominal) focus on the healing of the human immunodeficiency virus infe ction utilize modern molecular medicine. The only direction to do it, is the elemination of the human immunodeficiency virus from its reservoir the CD4 T-cells. I am considerably informed about the situation in Africa. I, myself, am a remedy _or_ abettor biocrystallographer at the stub for hiv/acquired immune deficiency syndrome networking KwaZulu-Natal. The AIDS syndrome is indirectly induced by the hiv infection. The direct cause of AIDS are the opportunist infections that first harm (preAIDS) and later on the whole destroy the immune system (late item of AIDS). For a triple-crown hiv elimination a conglutination tax shelter of the fresh biosynthezised yet neat CD4 T-cells is needed. Molecular medicine does the job figure new effective fusion inhibitors. It is my believe that new approaches in medicine pull up stakes provide a much better health protection for the people in the future.If you want to get a proficient essay, order it on our website:

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